Erythrocyte acid phosphatase polymorphism and haemolysis.
نویسندگان
چکیده
منابع مشابه
Haemolysis in experimental cholestasis: possible role of erythrocyte sialic acid.
Because previous studies have suggested that red cell membrane sialic acid might be a determinant of survival in vivo, we examined the relationship between haemolysis, erythrocyte membrane sialic acid, and hepatic neuraminidase (sialidase) levels in experimental cholestatic jaundice in rats. Treatment of normal rat erythrocytes with neuraminidase in vitro resulted in a significant reduction in ...
متن کاملErythrocyte autoantibodies, autoimmune haemolysis, and carcinoma.
AIMS To examine a large series of patients in whom both red cell autoantibodies and carcinoma are present; and to determine whether this rare occurrence is a true association or a chance event. METHODS The laboratory records of 160 patients (76 men, 84 women; mean age 68 years) with erythrocyte autoantibodies and confirmed carcinoma were examined for site of tumour origin and clinical and imm...
متن کاملErythrocyte autoantibodies, autoimmune haemolysis, and myelodysplastic syndromes.
Immunohaematological investigations were carried out in 46 patients with erythrocyte autoantibodies associated with myelodysplastic syndromes. Eight patients had refractory anaemia, 17 refractory anaemia with ring sideroblasts, 11 refractory anaemia with excess of blasts, four chronic myelomonocytic leukaemia, five refractory anaemia with excess of blasts in transformation and one could not be ...
متن کاملAssociation of erythrocyte acid phosphatase phenotypes with myopia
Acid phosphatase is a polymorphic nonspecific orthophosphate monoesterase which catalyses the cleaving of phosphoric acid and subsequent breakdown of several monophosphoric esters under acidic pH conditions. Acid phosphatase has a physiologic function as a flavin mononucleotide phosphatase (FMN) and regulates the intracellular concentrations of flavin coenzymes that are electron carriers in the...
متن کاملSmall quantities of erythrocyte bound immunoglobulins and autoimmune haemolysis.
Enzyme linked and radioimmune direct antiglobulin tests (DAGTs) were used to assess red cell bound IgG, IgA, and IgM in 585 patients referred to an immunohaematology reference centre. One hundred and fifty eight patients with less than or equal to 200 mol IgG and small amounts of IgA and IgM coating their red cells were studied in detail. The presence of autoimmune haemolysis was determined fro...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1972
ISSN: 1468-6244
DOI: 10.1136/jmg.9.4.434